Leaflet BUSULFAN ACCORD 6mg / ml concentrate for solution for infusion
Indicated for: conditioning before transplantation; hematologic malignancies
Route of administration: infusion
Substance: busulfan (alkylating antineoplastic agent)
ATC: L01AB01 (Antineoplastic and immunomodulating agents | Alkylating agents | Alkyl sulfonates)
This medicine may affect fertility.
Dose adjustment may be needed in liver disease.
Handle with special care.
Effective contraception is required during treatment.
Do not use this medicine while breastfeeding.
Do not use this medicine during pregnancy.
This medicine may affect the liver.
This medicine may have important interactions with other medicines.
This medicine may lower blood cell counts.
This medicine is subject to additional monitoring.
Periodic laboratory tests may be required during treatment.
Stop taking the medicine and seek urgent medical help if a severe rash occurs.
Busulfan is a chemotherapeutic medication primarily used for the treatment of chronic myeloid leukemia (CML) and as part of conditioning regimens prior to hematopoietic stem cell transplantation. It is an alkylating agent that interferes with the DNA of cancer cells, inhibiting cell division and causing cell death.
The medication is administered orally or intravenously, as directed by a doctor. The dosage and duration of treatment are adjusted based on the type of cancer, the patient's overall condition, and their response to treatment.
Common side effects include nausea, vomiting, diarrhea, fatigue, and decreased blood cell counts, which may increase the risk of infections. In rare cases, more severe adverse effects such as pulmonary toxicity, hepatotoxicity, or infertility may occur.
Busulfan is not recommended for pregnant or breastfeeding women, as it may affect fetal development. Patients should inform their doctor about all medications they are taking to avoid drug interactions. Additionally, regular monitoring during treatment is essential to detect and manage potential adverse effects.
General data about BUSULFAN ACCORD 6mg / ml
- Substance: busulfan
- Date of latest medicines list: 01-06-2026
- Product code: W65792001
- Concentration: 6mg / ml
- Pharmaceutical form: concentrate for solution for infusion
- Quantity: 1
- Product type: Generic medicine
- Price: 1196.75 RON
- Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Pharmaceutical forms available for busulfan
Concentrations available for busulfan
- 2mg
- 6mg/ml