Leaflet BIXTONIM XYLO DUO 1mg / 50mg / ml nasal spray, solution


Indicated for: nasal congestion; rhinitis

Substance: xylometazoline + dexpanthenol (adrenergic decongestant + wound-healing agent)

ATC: R01AB06 (Respiratory system | Decongestants and other nasal preparations for topical use | Sympathomimetics, combinations excl. corticosteroids)

The combination of xylometazoline and dexpanthenol is used for the symptomatic treatment of nasal congestion and for protecting irritated nasal mucosa. Xylometazoline is a nasal decongestant that works by constricting blood vessels in the nasal mucosa, thereby reducing swelling and congestion. Dexpanthenol is a derivative of pantothenic acid, known for its regenerative and moisturizing properties for the nasal mucosa.

This combination is administered as a nasal spray, usually 2-3 times a day, depending on the severity of symptoms. It is intended for short-term use, typically no more than 7 days, to avoid the risk of rebound rhinitis.

Common side effects include nasal dryness, mucosal irritation, and a burning sensation. In rare cases, severe adverse reactions such as nosebleeds or allergic reactions may occur.

Patients using this combination should adhere to the recommended dosage and avoid prolonged use. The combination of xylometazoline and dexpanthenol provides an effective solution for relieving nasal congestion while protecting and regenerating the nasal mucosa, enhancing patient comfort.

General data about BIXTONIM XYLO DUO 1mg / 50mg / ml

  • Substance: xylometazoline + dexpanthenol
  • Date of last drug list: 01-02-2026
  • Commercial code: W71629001
  • Concentration: 1mg / 50mg / ml
  • Pharmaceutical form: nasal spray, solution
  • Quantity: 1
  • Product type: generic
  • Prescription restrictions: OTC - Over the Counter = medicines that do not require a prescription.

Marketing authorisation

  • Manufacturer: BIOFARM S.A. - ROMANIA
  • Holder: BIOFARM S.A. - ROMANIA
  • Number: 16389/2025/01
  • Shelf life: 2 years-after packaging for sale;dup prima deschidere a flac.-12 saptamâni

Concentrations available for xylometazoline + dexpanthenol

  • 0.5mg/50mg/ml
  • 1mg/50mg/ml