BEVACOMB 10mg / 160mg film-coated tablets medication leaflet

C09DB01 • amlodipine + valsartan • Cardiovascular system | Angiotensin II receptor blockers (ARBs), combinations | Angiotensin ii receptor blockers (arbs) and calcium channel blockers

The combination of amlodipine and valsartan is used to treat essential hypertension (high blood pressure) in patients who cannot control their blood pressure with a single medication. This combination helps reduce the risk of cardiovascular complications, such as heart attack or stroke.

Amlodipine is a calcium channel blocker that relaxes blood vessels, improving blood flow and lowering blood pressure. Valsartan is an angiotensin II receptor blocker (ARB) that blocks the effects of angiotensin II, a hormone that causes blood vessel constriction, thereby helping to lower blood pressure.

This combination is effective in reducing blood pressure through complementary mechanisms: amlodipine acts on the smooth muscles of blood vessels, while valsartan prevents hormonal effects that lead to vessel constriction. It is particularly indicated for patients requiring combination therapy for optimal blood pressure control.

Common side effects include dizziness, headache, swelling (especially in the ankles), fatigue, nausea, or palpitations. In rare cases, allergic reactions, severe hypotension, or kidney impairment may occur. Regular medical monitoring is essential to adjust the treatment if necessary.

Patients should strictly follow their doctor’s instructions regarding dosage and avoid excessive salt or alcohol consumption. It is also recommended to inform the doctor about other medications being taken or pre-existing conditions, such as kidney or liver impairment.