Indicated for: spasticity; muscle spasms
Route of administration: infusion
Substance: baclofen (muscle relaxant)
ATC: M03BX01 (Musculo-skeletal system | Muscle relaxants, centrally acting agents | Other centrally acting agents)
Baclofen is a muscle relaxant used in the treatment of spasticity associated with neurological conditions such as multiple sclerosis, spinal cord injuries, or cerebral palsy. It works by inhibiting exaggerated spinal reflexes, reducing muscle tone and painful spasms.
Baclofen is administered orally, usually 2-4 times daily, with the dose gradually adjusted to minimize side effects. In severe cases, it can be administered intrathecally via an implantable pump for more effective spasticity control.
Common side effects include drowsiness, dizziness, muscle weakness, and nausea. In rare cases, severe adverse reactions such as respiratory depression, confusion, or hypotension may occur. It is important to taper off the treatment gradually to avoid withdrawal symptoms.
Baclofen is a valuable therapeutic option for patients with severe spasticity, contributing to improved mobility and quality of life.