Take with food
Take this medicine with food.
Medicine information ATOVAQUON/PROGUANILHYDROCHLORID STADA 250mg / 100mg film-coated tablets
- Product code:
- W72162001
- Quantity:
- 12
- Indicated for:
- prevention and treatment of uncomplicated Plasmodium falciparum malaria
- Route of administration:
- oral
- Substance:
- atovaquone + proguanil (hydroxynaphthoquinone antimalarial+biguanide antimalarial)
- ATC
- P01BB51 — Antiparasitic products, insecticides and repellents | Antimalarials | Biguanides
Atovaquone + proguanil is an antiparasitic combination used to prevent malaria and treat uncomplicated malaria caused by Plasmodium falciparum. The two medicines block processes the parasite needs to survive. Selection depends on the travel destination, parasite resistance and the patient's health.
Take it by mouth with food or a milky drink at the same time each day. For prevention, start 1–2 days before entering the risk area, continue daily throughout the stay and for 7 days after leaving. The dose depends on body weight and whether the medicine is used for prevention or treatment; treatment follows a different schedule. Repeat the dose if vomiting occurs within one hour of taking it.
Possible side effects include abdominal pain, nausea, vomiting, diarrhoea, headache and dizziness. Severe allergic reactions, blistering rashes and signs of liver injury require urgent assessment. This combination must not be used for prevention in severe kidney impairment. Tell the doctor about pregnancy, breastfeeding and medicines such as warfarin or rifampicin.
The medicine does not provide complete protection: use insect repellent, protective clothing and mosquito nets. Fever during the trip or after returning requires prompt medical assessment, even when preventive doses were taken correctly. Persistent diarrhoea or vomiting may reduce protection and should be discussed with the doctor.
Take it by mouth with food or a milky drink at the same time each day. For prevention, start 1–2 days before entering the risk area, continue daily throughout the stay and for 7 days after leaving. The dose depends on body weight and whether the medicine is used for prevention or treatment; treatment follows a different schedule. Repeat the dose if vomiting occurs within one hour of taking it.
Possible side effects include abdominal pain, nausea, vomiting, diarrhoea, headache and dizziness. Severe allergic reactions, blistering rashes and signs of liver injury require urgent assessment. This combination must not be used for prevention in severe kidney impairment. Tell the doctor about pregnancy, breastfeeding and medicines such as warfarin or rifampicin.
The medicine does not provide complete protection: use insect repellent, protective clothing and mosquito nets. Fever during the trip or after returning requires prompt medical assessment, even when preventive doses were taken correctly. Persistent diarrhoea or vomiting may reduce protection and should be discussed with the doctor.
General data about ATOVAQUON/PROGUANILHYDROCHLORID STADA 250mg / 100mg
- Substance:
- atovaquone + proguanil
- Date of latest medicines list:
- 01-10-2026
- Product code:
- W72162001
- Strength:
- 250mg / 100mg
- Pharmaceutical form:
- film-coated tablets
- Quantity:
- 12
- Product type:
- Generic medicine
- Price:
- 106.98 RON
- Prescription status:
- P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.
Official documents
Professional information (SmPC) - Romanian
Patient leaflet - Romanian
Packaging and labelling information - Romanian
The correspondence between the document and the displayed text is unconfirmed.
- Source institution
- ANMDMR
- Document language
- Romanian
Warnings:
Driving impairment
This medicine may affect your ability to drive or use machines.
Dizziness / vertigo
This medicine may cause dizziness or vertigo.
Anaphylaxis
Risk of severe allergic reaction. Seek urgent medical help if serious symptoms occur.
General warning
Read the package leaflet before use.
Contraindicated during breastfeeding
Do not use this medicine while breastfeeding.
Hepatotoxicity
This medicine may affect the liver.
Major drug interactions
This medicine may have important interactions with other medicines.
Pregnancy warning
Use during pregnancy only on medical advice.
Pediatric warning
Use in children only as recommended in the leaflet or by a doctor.
Severe skin reactions
Stop taking the medicine and seek urgent medical help if a severe rash occurs.