Leaflet ASTONIN H 0.1mg tablets

Indicated for: adrenal insufficiency

Route of administration: oral

Substance: fludrocortisone (glucocorticoid)

ATC: H02AA02 (Systemic hormonal preparations, excluding sex hormones and insulins | Corticosteroids for systemic use, plain | Mineralocorticoids)

Precautions:
Glaucoma warning
Glaucoma warning

Use caution if you have glaucoma or increased eye pressure.

Hyperglycemia
Hyperglycemia

This medicine may increase blood sugar.

Immunosuppression / infection risk
Immunosuppression / infection risk

This medicine may increase the risk of infections.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Fludrocortisone is a corticosteroid medication used to treat conditions associated with adrenal insufficiency, such as Addison's disease, and to manage certain forms of orthostatic hypotension. It works by mimicking the effects of the hormone aldosterone, helping to regulate the body's salt and water balance, which contributes to maintaining normal blood pressure.

Fludrocortisone is taken orally, usually in tablet form, and the dosage is adjusted based on the patient's needs and response to treatment. It is primarily used to prevent excessive loss of sodium and water through urine and to maintain adequate potassium levels.

Side effects may include high blood pressure, edema (fluid retention), weight gain, muscle weakness, headaches, and, rarely, allergic reactions. Long-term use may increase the risk of osteoporosis, hypokalemia (low potassium levels), or other metabolic complications. It is important to take fludrocortisone as prescribed by a healthcare provider, and patients should be regularly monitored to prevent electrolyte imbalances and other adverse effects.

General data about ASTONIN H 0.1mg

  • Substance: fludrocortisone
  • Date of latest medicines list: 01-06-2026
  • Product code: W66284002
  • Concentration: 0.1mg
  • Pharmaceutical form: tablets
  • Quantity: 50
  • Product type: Original
  • Price: 110.96 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: P&G HEALTH AUSTRIA GMBH & CO. OG - AUSTRIA
  • Holder: MERCK ROMANIA SRL - ROMANIA
  • Number: 8004/2015/02
  • Shelf life: 3 years

Compensation lists for ASTONIN H 0.1mg Merck Sharp & Dohme

B - Sublist B with 50% discount from the reference price

Price

Copayment

Patient

110.96 RON

55.48 RON

55.48 RON

G22 (C1) - Endocrine diseases

Price

Copayment

Patient

110.96 RON

110.96 RON

0.00 RON

GX (C1) - GENERIC (used in compensation list, C1, for another diagnosis)

Price

Copayment

Patient

110.96 RON

110.96 RON

0.00 RON