Leaflet ARPLEXAM 10mg / 10mg / 2.5mg film-coated tablets
Indicated for: hypertension
Route of administration: oral
Substance: perindopril + amlodipine + indapamide (ACE inhibitor + calcium channel blocker + diuretic)
ATC: C09BX01 (Cardiovascular system | Ace inhibitors, combinations | Ace inhibitors, other combinations)
Dose adjustment may be needed in kidney disease.
Do not use this medicine during pregnancy.
May lower blood pressure and increase the risk of falls.
This medicine may have important interactions with other medicines.
Periodic laboratory tests may be required during treatment.
This medicine may change blood electrolyte levels.
The combination of perindopril, amlodipine, and indapamide is used to treat essential hypertension (high blood pressure) in patients requiring combination therapy. This combination helps lower blood pressure and prevent cardiovascular complications such as heart attack, stroke, or heart failure.
Perindopril is an angiotensin-converting enzyme (ACE) inhibitor that relaxes blood vessels and lowers blood pressure. Amlodipine is a calcium channel blocker that dilates blood vessels, improving blood flow and reducing blood pressure. Indapamide is a thiazide diuretic that removes excess salt and water from the body, reducing blood volume and, consequently, blood pressure.
This combination is recommended for patients who cannot control their blood pressure with a single medication or a combination of two drugs. Through the synergistic action of the three components, the treatment provides more effective blood pressure control and reduces the risk of cardiovascular complications.
Side effects may include dizziness, headache, swelling (especially in the ankles), nausea, fatigue, or muscle cramps. In rare cases, allergic reactions, severe hypotension, kidney, or liver problems may occur. Regular medical monitoring is essential to adjust the treatment if necessary.
Patients should strictly follow their doctor’s instructions regarding dosage and avoid excessive salt or alcohol consumption. It is also recommended to inform the doctor about other medications being taken or pre-existing conditions, such as kidney or liver impairment.
General data about ARPLEXAM 10mg / 10mg / 2.5mg
- Substance: perindopril + amlodipine + indapamide
- Date of latest medicines list: 01-07-2015
- Product code: W61408001
- Concentration: 10mg / 10mg / 2.5mg
- Pharmaceutical form: film-coated tablets
- Quantity: 30
- Product type: Generic medicine
- Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.
Pharmaceutical forms available for perindopril + amlodipine + indapamide
Concentrations available for perindopril + amlodipine + indapamide
- 10mg/10mg/2.5mg
- 10mg/5mg/2.5mg
- 2.5mg/5mg/0.625mg
- 4mg/1.25mg/10mg
- 5mg/10mg/1.25mg
- 5mg/5mg/1.25mg