Leaflet ARGANOVA 1mg / ml solution for infusion

Indicated for: heparin-induced thrombocytopenia; anticoagulation

Route of administration: infusion

Substance: argatroban (anticoagulant)

ATC: B01AE03 (Blood and blood forming organs | Antithrombotic agents | Direct thrombin inhibitors)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Additional monitoring
Additional monitoring

This medicine is subject to additional monitoring.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.

Argatroban is an anticoagulant used in the treatment and prevention of thrombosis, particularly in patients with heparin-induced thrombocytopenia (HIT). It is a direct thrombin inhibitor that works by blocking the enzymatic activity of thrombin, thereby preventing blood clot formation.

Argatroban is administered intravenously and is commonly used in critical situations such as deep vein thrombosis or pulmonary embolism, especially in patients who cannot use heparin. The dose is adjusted based on coagulation parameters such as activated clotting time (ACT).

Common side effects include bleeding, nausea, headache, and hypotension. Administration must be performed under strict medical supervision, with careful monitoring of coagulation parameters.

Argatroban is an essential medication for managing thrombotic complications, providing a safe and effective alternative for patients at high risk of thrombosis.

General data about ARGANOVA 1mg / ml

  • Substance: argatroban
  • Date of latest medicines list: 01-06-2024
  • Product code: W68780001
  • Concentration: 1mg / ml
  • Pharmaceutical form: solution for infusion
  • Quantity: 4
  • Product type: Generic medicine
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: ALFASIGMA S.P.A. - ITALIA
  • Holder: HYPERICUM S.R.L. - ROMANIA
  • Number: 711/2022/01
  • Shelf life: 3 years

Pharmaceutical forms available for argatroban

Concentrations available for argatroban

  • 100mg/ml
  • 1mg/ml