Indicated for: Parkinson's disease
Substance: apomorphine (antiparkinsonian agent)
ATC: N04BC07 (Nervous system | Dopaminergic agents | Dopamine agonists)
Apomorphine is a dopamine receptor agonist used in the treatment of Parkinson's disease, particularly for managing motor block episodes (off episodes). It works by directly stimulating dopamine receptors in the brain, alleviating motor symptoms such as rigidity, tremor, and bradykinesia.
Apomorphine is administered as subcutaneous injections or through continuous infusion pumps, depending on the patient's needs. It is often used as a rescue therapy for patients who do not respond adequately to oral treatments.
Common side effects include nausea, vomiting, orthostatic hypotension, and drowsiness. In rare cases, allergic reactions or compulsive behaviors may occur. It is important for treatment to be initiated under strict medical supervision.
Apomorphine is a valuable therapeutic option for patients with Parkinson's disease, helping to improve quality of life by reducing motor block episodes.