Leaflet AMITRIPTILINA ARENA 25mg film-coated tablets

Indicated for: depression; neuropathic pain

Route of administration: oral

Substance: amitriptyline (antidepressant)

ATC: N06AA09 (Nervous system | Antidepressants | Non-selective monoamine reuptake inhibitors)

Precautions:
Driving impairment
Driving impairment

This medicine may affect your ability to drive or use machines.

Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Seizure risk
Seizure risk

This medicine may increase the risk of seizures.

Suicidal ideation / mental changes
Suicidal ideation / mental changes

Seek medical help if suicidal thoughts or major behavior changes occur.

Withdrawal / do not stop abruptly
Withdrawal / do not stop abruptly

Do not stop treatment abruptly without medical advice.

Drowsiness / sedation
Drowsiness / sedation

This medicine may cause drowsiness or reduced alertness.

Amitriptyline is a tricyclic antidepressant primarily used to treat depression, but it is also effective for other conditions such as neuropathic pain, chronic migraines, and anxiety disorders. It works by increasing the levels of serotonin and norepinephrine in the brain, neurotransmitters that play a key role in regulating mood and pain.

Amitriptyline is taken orally, usually once daily in the evening, due to its sedative effect. The dosage is gradually adjusted based on the patient's response and the severity of symptoms.

Common side effects include drowsiness, dry mouth, constipation, dizziness, and weight gain. In rare cases, severe adverse reactions such as cardiac arrhythmias, seizures, or withdrawal symptoms upon abrupt discontinuation may occur.

Patients taking amitriptyline should be monitored for signs of worsening depression or the emergence of suicidal thoughts, especially at the beginning of treatment. Additionally, the medication may interact with other drugs, such as MAO inhibitors or alcohol, requiring caution. Amitriptyline is an effective option for managing depression and chronic pain, but its use must be carefully supervised by a specialist physician.

General data about AMITRIPTILINA ARENA 25mg

  • Substance: amitriptyline
  • Date of latest medicines list: 01-06-2026
  • Product code: W52017001
  • Concentration: 25mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 50
  • Product type: Generic medicine
  • Price: 17.84 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: ARENA GROUP S.A. - ROMANIA
  • Holder: ARENA GROUP S.A. - ROMANIA
  • Number: 13252/2020/01
  • Shelf life: 2 years

Pharmaceutical forms available for amitriptyline

Concentrations available for amitriptyline

  • 25mg
  • 50mg

Compensation lists for AMITRIPTILINA ARENA 25mg Arena

A - Sublist A with 90% discount from the reference price

Price

Copayment

Patient

17.84 RON

16.06 RON

1.78 RON