Leaflet AMBRISENTAN ZENTIVA 5mg film-coated tablets

Product code:
W67458001
Quantity:
10
Indicated for:
pulmonary arterial hypertension
Route of administration:
oral
Substance:
ambrisentan (vasodilator)
ATC
C02KX02 — Cardiovascular system | Other antihypertensives | Antihypertensives for pulmonary arterial hypertension

Precautions:

Dizziness / vertigo

Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Hypotension / fall risk

Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Ambrisentan is a medication used in the treatment of pulmonary arterial hypertension (PAH), a condition characterized by increased pressure in the pulmonary arteries, leading to shortness of breath, fatigue, and other symptoms. It belongs to a class of drugs called endothelin receptor antagonists and works by blocking the effects of endothelin-1, a substance that causes blood vessel constriction and increased blood pressure.

Ambrisentan is taken orally, usually once daily, with the dosage adjusted based on the patient's response to treatment. It is often used in combination with other PAH medications, such as phosphodiesterase-5 inhibitors or prostanoids.

Side effects may include headaches, fluid retention, nasal congestion, and anemia. In rare cases, more severe adverse effects, such as liver function impairment, may occur.

Patients taking ambrisentan should undergo regular monitoring for liver function and hemoglobin levels. Additionally, the medication is contraindicated during pregnancy as it can cause birth defects. Ambrisentan is an important option for managing PAH, improving patients' quality of life.

General data about AMBRISENTAN ZENTIVA 5mg

Substance:
ambrisentan
Date of latest medicines list:
01-04-2021
Product code:
W67458001
Concentration:
5mg
Pharmaceutical form:
film-coated tablets
Quantity:
10
Product type:
Generic medicine
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
GENEPHARM S.A. - GRECIA
Holder:
ZENIVA, K.S. - REP. CEHA
Number:
13712/2021/01
Shelf life:
3 years

Concentrations available for ambrisentan

  • 10mg
  • 5mg