Leaflet AMBISOME LIPOSOMAL AMPHOTERICIN B 50mg powder for concentrate for dispersion for infusion

Product code:
W71201002
Quantity:
10
Indicated for:
fungal infections
Route of administration:
infusion
Substance:
amphotericin B (antifungal)
ATC
J02AA01 — Antiinfectives for systemic use | Antimycotics for systemic use | Antimycotics for systemic use | Antibiotics

Precautions:

Dose adjustment in hepatic impairment

Dose adjustment in hepatic impairment

Dose adjustment may be needed in liver disease.

Nephrotoxicity

Nephrotoxicity

This medicine may affect the kidneys.

Amphotericin B is an antifungal medication used to treat severe and potentially life-threatening fungal infections. It is effective against a wide range of fungi, including Candida, Aspergillus, and Cryptococcus, and is used in systemic or invasive infections such as cryptococcal meningitis or invasive aspergillosis.

This medication works by binding to ergosterol in the fungal cell membrane, leading to the destruction of fungal cells. It is available as an injectable solution and is administered intravenously, usually in a hospital setting under strict medical supervision.

Amphotericin B can cause significant side effects, including fever, chills, nausea, vomiting, kidney damage, and electrolyte imbalances. For this reason, its use is reserved for severe cases, and patients require close monitoring during treatment.

Liposomal formulations of amphotericin B are better tolerated and have an improved safety profile, making them preferred in certain situations.

General data about AMBISOME LIPOSOMAL AMPHOTERICIN B 50mg

Substance:
amphotericin B
Date of latest medicines list:
01-06-2026
Product code:
W71201002
Concentration:
50mg
Pharmaceutical form:
powder for concentrate for dispersion for infusion
Quantity:
10
Product type:
Generic medicine
Price:
6078.62 RON
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
GILEAD SCIENCES IRELAND UC - IRLANDA
Holder:
GILEAD SCIENCES IRELAND UC - IRLANDA
Number:
15/2025/02
Shelf life:
4 years dupa ambalare pt. comecializare; after the first opening-it is used immediately

Concentrations available for amphotericin B

  • 50mg
  • 50mg/5ml
  • 5mg/ml

Compensation lists for AMBISOME LIPOSOMAL AMPHOTERICIN B 50mg Gilead

NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment

Price
6078.62 RON
Copayment
6078.62 RON
Patient
0.00 RON