Leaflet AKLIEF 50mcg/G cream

Indicated for: acne

Route of administration: cutaneous

Substance: trifaroten (retinoid)

ATC: D10AD06 (Dermatologicals | Anti-acne preparations for topical use | Retinoids for topical use in acne)

Trifarotene is a fourth-generation retinoid used in the treatment of acne vulgaris and other dermatological conditions characterized by abnormal keratinization. It works by selectively binding to RAR-gamma receptors, which are involved in regulating cellular differentiation and proliferation in the skin.

Trifarotene is available as a topical cream and is applied directly to the affected skin, usually once daily in the evening. It is effective in reducing inflammatory and non-inflammatory acne lesions, as well as improving skin texture.

Common side effects include skin dryness, erythema, peeling, and a burning or stinging sensation at the application site. Patients are advised to use sunscreen, as trifarotene may increase skin sensitivity to UV radiation.

Trifarotene is an innovative therapeutic option for patients with acne, offering a favorable safety and efficacy profile with significant benefits for skin health.

General data about AKLIEF 50mcg/G

  • Substance: trifaroten
  • Date of latest medicines list: 01-06-2026
  • Product code: W68352004
  • Concentration: 50mcg / g
  • Pharmaceutical form: cream
  • Quantity: 1
  • Product type: Original
  • Price: 179.75 RON
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: GALDERMA LABORATORIUM GMBH - GERMANIA
  • Holder: GALDERMA INTERNATIONAL - FRANTA
  • Number: 14177/2021/04
  • Shelf life: 2 years-after packaging for sale;6 months-after the first opening of the tube sau flac.