AFLAMIL 100mg tablets medication leaflet

M01AB16 • aceclofenac • Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Acetic acid derivatives and related substances

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with musculoskeletal and rheumatic conditions. It is indicated for conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Aceclofenac is a derivative of diclofenac, with improved gastrointestinal tolerability.

It works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins, substances involved in inflammation, pain, and fever. This mechanism helps relieve pain and reduce inflammation.

The medication is taken orally, usually in the form of tablets, with a recommended dose of 100 mg twice daily, as directed by a doctor. It is important to take it after meals to minimize the risk of gastrointestinal irritation.

Common side effects include gastrointestinal disturbances such as nausea, abdominal pain, diarrhea, or constipation. Rarely, more severe reactions such as gastric ulcers, gastrointestinal bleeding, allergic reactions, or kidney and liver impairment may occur.

Aceclofenac should be used with caution in patients with a history of gastric ulcers, renal insufficiency, hypertension, or cardiovascular diseases. It is also important to avoid concurrent use with other NSAIDs or anticoagulants, as this may increase the risk of bleeding.