Leaflet ADVIL DUO 500mg/200mg 200mg / 500mg film-coated tablets


Indicated for: pain; fever

Route of administration: oral

Substance: paracetamol + ibuprofen (analgesic and antipyretic + nonsteroidal anti-inflammatory drug)

ATC: N02BE51 (Nervous system | Other analgesics and antipyretics | Anilides)

Precautions:
Hepatotoxicity
Hepatotoxicity

This medicine may affect the liver.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Nephrotoxicity
Nephrotoxicity

This medicine may affect the kidneys.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Bleeding risk
Bleeding risk

This medicine may increase the risk of bleeding.

Ulcer / gastrointestinal bleeding
Ulcer / gastrointestinal bleeding

This medicine may increase the risk of ulcer or gastrointestinal bleeding.

Paracetamol + ibuprofen is a combination medication used to treat moderate to severe pain and fever. This combination is effective in relieving pain and inflammation and is commonly used for conditions such as headaches, dental pain, muscle pain, postoperative pain, or fever associated with infections.

Paracetamol acts as an analgesic and antipyretic, reducing pain and fever, while ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), reduces inflammation and pain by inhibiting prostaglandin production. The combination of the two drugs provides a synergistic effect, making it more effective than taking each drug separately.

Side effects may include nausea, heartburn, dizziness, or, in rare cases, allergic reactions. Long-term use or high doses may increase the risk of liver damage (due to paracetamol) or gastric irritation and ulcers (due to ibuprofen). It is important to take this combination as directed by a doctor or pharmacist.

General data about ADVIL DUO 500mg/200mg 200mg / 500mg

  • Substance: paracetamol + ibuprofen
  • Date of last drug list: 01-05-2026
  • Commercial code: W71800001
  • Concentration: 200mg / 500mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 10
  • Product type: generic
  • Prescription restrictions: OTC - Over the Counter = medicines that do not require a prescription.

Marketing authorisation

  • Manufacturer: ZAKLADY FARMACEUTYCZNE POLPHARMA S.A. - POLONIA
  • Holder: HALEON ROMANIA S.R.L. - ROMANIA
  • Number: 16535/2026/01
  • Shelf life: 3 years

Pharmaceutical forms available for paracetamol + ibuprofen

Concentrations available for paracetamol + ibuprofen

  • 1000mg/300mg
  • 200mg/500mg
  • 32mg/ml+9.6mg/ml
  • 500mg/150mg
  • 500mg/200mg