Leaflet ACTILYSE 50mg powder and solvent for solution for injection / infusion

Product code:
W00257001
Quantity:
1
Indicated for:
thrombolysis; myocardial infarction; ischemic stroke
Route of administration:
injectable / infusion
Substance:
alteplase (thrombolytic)
ATC
B01AD02 — Blood and blood forming organs | Antithrombotic agents | Antithrombotic agents | Enzymes
Alteplase is a thrombolytic medication used to dissolve blood clots that cause acute ischemic strokes, acute myocardial infarctions, or severe pulmonary embolisms. It is a recombinant form of tissue plasminogen activator (tPA), an enzyme that converts plasminogen into plasmin, a substance that breaks down fibrin in clots.

Alteplase is administered intravenously, usually within the first few hours of symptom onset, to maximize its effectiveness. Timing is critical, as its efficacy decreases significantly after a certain period.

Side effects may include bleeding, including intracranial hemorrhage, allergic reactions, or hypotension. For this reason, the use of alteplase requires careful risk-benefit assessment and continuous monitoring during administration.

Patients must be evaluated for contraindications, such as a history of recent bleeding, major surgery, or uncontrolled hypertension. Alteplase is a life-saving medication, but its use must be strictly supervised by specialized medical personnel.

General data about ACTILYSE 50mg

Substance:
alteplase
Date of latest medicines list:
01-06-2026
Product code:
W00257001
Concentration:
50mg
Pharmaceutical form:
powder and solvent for solution for injection / infusion
Quantity:
1
Product type:
Original
Price:
1837.62 RON
Prescription status:
S — Medicines dispensed with a restricted medical prescription, reserved for use in certain specialized fields.

Marketing authorisation

Manufacturer:
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG - GERMANIA
Holder:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - GERMANIA
Number:
2022/2009/01
Shelf life:
3 years

Compensation lists for ACTILYSE 50mg Boehringer

NHP 9.3 (C2) - Liver Transplant

Price
1837.62 RON
Copayment
1837.62 RON
Patient
0.00 RON