Leaflet ACICLOVIR AUROBINDO 400mg tablets


Indicated for: herpes virus infections

Route of administration: oral

Substance: acyclovir (antiviral)

ATC: J05AB01 (Antiinfectives for systemic use | Direct acting antivirals | Nucleosides and nucleotides excl. reverse transcriptase inhibitors)

Precautions:
Dose adjustment in renal impairment
Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Major drug interactions
Major drug interactions

This medicine may have important interactions with other medicines.

Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Acyclovir is an antiviral medication used to treat infections caused by herpes viruses, such as herpes simplex (HSV) and varicella-zoster (VZV). It is indicated for the treatment of oral and genital herpes, chickenpox, and shingles, as well as for preventing recurrences in patients with recurrent herpes infections.

Acyclovir works by inhibiting viral DNA replication, thereby reducing the severity and duration of symptoms. It can be administered orally, topically (as a cream), or intravenously, depending on the severity of the infection.

Common side effects include nausea, diarrhea, headaches, or local irritation (with topical use). In rare cases, intravenous administration may cause kidney damage or severe allergic reactions. It is important for patients to stay well-hydrated during treatment to reduce the risk of kidney toxicity.

Acyclovir is effective in managing herpes infections but does not cure the infection, as the virus remains dormant in the body. Treatment should be started as early as possible after symptom onset to maximize effectiveness.

General data about ACICLOVIR AUROBINDO 400mg

  • Substance: acyclovir
  • Date of last drug list: 01-06-2023
  • Commercial code: W65784008
  • Concentration: 400mg
  • Pharmaceutical form: tablets
  • Quantity: 10
  • Product type: generic
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: APL SWIFT SERVICES (MALTA) LIMITED - MALTA
  • Holder: AUROBINDO PHARMA ROMANIA S.R.L. - ROMANIA
  • Number: 11624/2019/01
  • Shelf life: 2 years

Concentrations available for acyclovir

  • 200mg
  • 250mg
  • 25mg/ml
  • 3%
  • 30mg/g
  • 400mg
  • 5%
  • 500mg
  • 50mg
  • 50mg/g

Combinations with other substances