Leaflet ACENOCUMAROL AUROBINDO 4mg tablets

Product code:
W69283001
Quantity:
20
Indicated for:
prevention and treatment of thromboembolism
Route of administration:
oral
Substance:
acenocoumarol (anticoagulant)
ATC
B01AA07 — Blood and blood forming organs | Antithrombotic agents | Antithrombotic agents | Vitamin K antagonists

Precautions:

Dose adjustment in renal impairment

Dose adjustment in renal impairment

Dose adjustment may be needed in kidney disease.

Contraception required

Contraception required

Effective contraception is required during treatment.

Contraindicated during pregnancy

Contraindicated during pregnancy

Do not use this medicine during pregnancy.

Narrow therapeutic index

Narrow therapeutic index

The dose must be followed strictly.

Major drug interactions

Major drug interactions

This medicine may have important interactions with other medicines.

Additional monitoring

Additional monitoring

This medicine is subject to additional monitoring.

Requires periodic laboratory tests

Requires periodic laboratory tests

Periodic laboratory tests may be required during treatment.

Bleeding risk

Bleeding risk

This medicine may increase the risk of bleeding.

Teratogenic / fetal risk

Teratogenic / fetal risk

This medicine may affect fetal development.

Acenocoumarol is an anticoagulant medication from the coumarin class, used for the prevention and treatment of thrombosis and embolism. It is indicated for conditions such as deep vein thrombosis, pulmonary embolism, atrial fibrillation, and the prevention of thromboembolic complications in patients with prosthetic heart valves.

Acenocoumarol works by inhibiting the synthesis of vitamin K-dependent clotting factors (factors II, VII, IX, and X), thereby reducing the blood's ability to form clots.

The dosage is individually adjusted based on regular monitoring of the INR (International Normalized Ratio) to maintain a balance between preventing clot formation and minimizing the risk of bleeding.

Common side effects include an increased risk of bleeding (e.g., nosebleeds, gum bleeding, or gastrointestinal bleeding), easy bruising, and, in rare cases, skin necrosis. Patients should avoid excessive consumption of foods rich in vitamin K (such as spinach, broccoli, or cabbage), as these can reduce the medication's effectiveness.

Acenocoumarol requires careful monitoring and frequent dose adjustments. Patients should inform their doctor about any other medications or supplements they are taking, as interactions can affect blood clotting.

General data about ACENOCUMAROL AUROBINDO 4mg

Substance:
acenocoumarol
Date of latest medicines list:
01-01-2023
Product code:
W69283001
Concentration:
4mg
Pharmaceutical form:
tablets
Quantity:
20
Product type:
Generic medicine
Prescription status:
P-RF — Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

Manufacturer:
APL SWIFT SERVICES (MALTA) LTD. - MALTA
Holder:
AUROBINDO PHARMA ROMANIA S.R.L. - ROMANIA
Number:
14757/2022/01
Shelf life:
3 years

Concentrations available for acenocoumarol

  • 2mg
  • 4mg