Anatomical Therapeutic Chemical • L01XX81 • nirogacestat

A Alimentary tract and metabolism

B Blood and blood forming organs

C Cardiovascular system

D Dermatologicals

G Genito urinary system and sex hormones

H Systemic hormonal preparations, excluding sex hormones and insulins

J Antiinfectives for systemic use

L Antineoplastic and immunomodulating agents

L01 Antineoplastic agents

L01A Alkylating agents

L01B Antimetabolites

L01C Plant alkaloids and other natural products

L01D Cytotoxic antibiotics and related substances

L01E Protein kinase inhibitors

L01F Monoclonal antibodies and antibody drug conjugates

L01X Other antineoplastic agents

L01XA Platinum compounds

L01XB Methylhydrazines

L01XC Monoclonal antibodies

L01XD Sensitizers used in photodynamic/radiation therapy

L01XF Retinoids for cancer treatment

L01XG Proteasome inhibitors

L01XH Histone deacetylase (HDAC) inhibitors

L01XJ Hedgehog pathway inhibitors

L01XK Poly (ADP-ribose) polymerase (PARP) inhibitors

L01XL Antineoplastic cell and gene therapy

L01XM Isocitrate dehydrogenase (IDH) inhibitors

L01XU Other antineoplastic agents (cont.)

L01XX Other antineoplastic agents

L01XX02 asparaginase Indicated for: leukemia

L01XX05 hydroxycarbamide Indicated for: myeloproliferative neoplasms; sickle cell disease

L01XX09 miltefosine Indicated for: leishmaniasis

L01XX11 estramustine Indicated for: cancer

L01XX14 tretinoin Indicated for: acne; acute promyelocytic leukemia

L01XX17 topotecan Indicated for: ovarian cancer; small cell lung cancer

L01XX19 irinotecan Indicated for: colorectal cancer

L01XX22 alitretinoin Indicated for: eczema; inflammatory dermatoses

L01XX23 mitotane Indicated for: adrenocortical carcinoma

L01XX24 pegaspargase Indicated for: cancer

L01XX25 bexarotene Indicated for: cutaneous T-cell lymphoma

L01XX27 arsenic trioxide Indicated for: acute promyelocytic leukemia

L01XX32 bortezomib Indicated for: multiple myeloma

L01XX33 celecoxib Indicated for: pain and inflammation

L01XX35 anagrelide Indicated for: essential thrombocythemia

L01XX41 eribulin Indicated for: breast cancer

L01XX42 panobinostat Indicated for: cancer

L01XX43 vismodegib Indicated for: cancer

L01XX44 aflibercept Indicated for: macular degeneration; diabetic macular edema

L01XX45 carfilzomib Indicated for: multiple myeloma

L01XX46 olaparib Indicated for: cancer

L01XX50 ixazomib Indicated for: cancer

L01XX52 venetoclax Indicated for: hematologic malignancies

L01XX73 sotorasib Indicated for: non-small cell lung cancer

L01XX74 belzutifan Indicated for: tumors associated with von Hippel-Lindau disease

L01XX75 tebentafusp Indicated for: melanoma

L01XX77 adagrasib Indicated for: non-small cell lung cancer

L01XX81 nirogacestat Indicated for: desmoid tumors

L01XY Combinations of antineoplastic agents

L02 Endocrine therapy

L03 Immunostimulants

L04 Immunosuppressants

M Musculo-skeletal system

N Nervous system

P Antiparasitic products, insecticides and repellents

R Respiratory system

S Sensory organs

V Various