J02AC03 • voriconazole • Antiinfectives for systemic use | Antimycotics for systemic use | Triazole derivatives
Voriconazole is an antifungal medication used to treat severe fungal infections, such as invasive aspergillosis, esophageal candidiasis, and other fungal infections caused by Candida or Fusarium species. It belongs to the triazole class and works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to fungal destruction.
Voriconazole is particularly indicated for immunocompromised patients, such as those with organ transplants, cancer, or other conditions that weaken the immune system. It is available in tablet form, oral suspension, or intravenous injection, and the dosage is adjusted based on the patient’s weight and the severity of the infection.
Common side effects include nausea, vomiting, abdominal pain, skin rashes, visual disturbances (such as blurred vision or light sensitivity), and elevated liver enzymes. Rarely, more serious reactions such as severe hepatotoxicity, allergic reactions, or cardiac arrhythmias may occur.
Treatment with voriconazole requires careful monitoring, including regular liver and kidney function tests. Patients should avoid prolonged sun exposure, as voriconazole can increase skin sensitivity to UV radiation. The medication should be taken as prescribed by a doctor, and dose adjustments should be made cautiously.
Substance: voriconazole
Date of last drug list: 01-06-2025
Commercial code: W61628005
Concentration: 200mg
Pharmaceutical form: tablets
Quantity: 28
Product type: generic
Price: 551.73 RON
Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).
Manufacturer: ZENTIVA S.A. - ROMANIA
Holder: ZENTIVA, K.S. - REPUBLICA CEHA
Number: 12103/2019/05
Shelf life: 2 years
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