ROXAMPEX 20mg / 5mg / 8mg tablets medication leaflet

C10BX14 • rosuvastatin + amlodipine + perindopril • Cardiovascular system | Lipid modifying agents, combinations | Lipid modifying agents in combination with other drugs

Rosuvastatin+amlodipine+perindopril is a combination medication used for the treatment of dyslipidemia, hypertension, and the prevention of cardiovascular diseases. Rosuvastatin lowers LDL cholesterol and triglycerides, amlodipine is a calcium channel blocker that relaxes blood vessels and lowers blood pressure, and perindopril is an angiotensin-converting enzyme (ACE) inhibitor that helps reduce blood pressure and provides cardiovascular protection.

This combination is taken orally, usually once daily, and is indicated for patients at high cardiovascular risk, including those with hypertension and associated dyslipidemia. It is commonly used to reduce the risk of major cardiovascular events such as myocardial infarction and stroke.

Common side effects include dizziness, headache, nausea, and muscle pain. In rare cases, severe adverse reactions such as kidney failure, peripheral edema, or rhabdomyolysis may occur. Regular monitoring of renal function, blood pressure, and lipid profile is essential.

Rosuvastatin+amlodipine+perindopril is a comprehensive therapeutic option for patients with multiple cardiovascular risk factors, offering significant benefits in a single administration.