OPHTASONE ophthalmic drops solution medication leaflet

S01CA05 • gentamicin + betamethasone • Sensory organs | Antiinflammatory agents and antiinfectives in combination | Corticosteroids and antiinfectives in combination

The combination of gentamicin and betamethasone is used to treat skin or inflammatory infections caused by susceptible bacteria and requiring inflammation reduction. It is commonly available as creams, ointments, or drops (ophthalmic or otic), depending on the location of the condition.

- Gentamicin is an aminoglycoside antibiotic that works by inhibiting bacterial protein synthesis, providing a bactericidal effect against gram-negative and some gram-positive bacteria.
- Betamethasone is a potent corticosteroid that reduces inflammation, itching, and redness by suppressing the body's inflammatory and immune response.

This combination is indicated for conditions such as infected dermatitis, infected eczema, otitis externa, or bacterial conjunctivitis associated with severe inflammation.

Side effects may include local irritation, burning sensation, dryness, or allergic reactions. Prolonged use of corticosteroids can lead to skin thinning, stretch marks, or secondary infections. When used near the eyes, there is a risk of increased intraocular pressure or cataract development.

Patients should strictly follow their doctor’s instructions regarding the duration and method of application. It is important not to use this combination long-term or on large areas of skin without medical supervision, as it may increase the risk of systemic side effects.