OLOPEG concentrate for oral solution medication leaflet

A06AD15 • macrogol • Alimentary tract and metabolism | Drugs for constipation | Osmotically acting laxatives

Macrogol, also known as polyethylene glycol (PEG), is an osmotic laxative used to treat acute and chronic constipation. It works by drawing water into the intestine, which helps soften the stool and facilitate its passage. It is a widely used and well-tolerated medication.

Macrogol is effective in managing functional constipation, including in elderly patients or those with chronic conditions. It is often recommended as a first-line treatment due to its safety and efficacy. Unlike other laxatives, macrogol does not cause significant abdominal cramping.

In cases of severe constipation, macrogol can be combined with other laxatives to improve outcomes. It is also used for bowel cleansing before medical procedures such as colonoscopy. The dosage and duration of treatment are adjusted based on the patient’s needs.

Macrogol is well-tolerated, with rare and mild side effects such as bloating or abdominal discomfort. It is considered safe for long-term use, but it is important to use it as directed by a doctor, especially in children or pregnant women.

Although effective for constipation, macrogol does not address its underlying causes. Patients are encouraged to maintain a fiber-rich diet, drink plenty of fluids, and lead an active lifestyle to prevent constipation recurrence.