MACITENTAN ZENTIVA 10mg film-coated tablets medication leaflet

C02KX04 macitentan • Cardiovascular system | Other antihypertensives | Antihypertensives for pulmonary arterial hypertension

Macitentan is a medication used for the treatment of pulmonary arterial hypertension (PAH). It acts as an endothelin receptor antagonist, reducing pressure in the pulmonary blood vessels and improving exercise capacity.

The medication is taken orally, usually once daily, and is intended for long-term use under the supervision of a specialist. It is important to follow the treatment regimen to achieve the best results.

Side effects may include headaches, fluid retention, or anemia. In rare cases, elevated liver enzymes or allergic reactions may occur.

Macitentan is not recommended for pregnant women or patients with severe liver impairment. Regular monitoring of liver function is required during treatment.

General data about MACITENTAN ZENTIVA 10mg

Substance: macitentan

Commercial code: W71847001

Concentration: 10mg

Pharmaceutical form: film-coated tablets

Product type: generic

Prescription restrictions: S - Medicines prescription reserved for use in certain specialized fields.

Marketing authorisation

Manufacturer: PHARMADOX HEALTHCARE LIMITED - MALTA

Holder: ZENTIVA, K.S. - REPUBLICA CEHA

Number: 16558/2026/01

Shelf life: 3 years

Pharmaceutical forms available for macitentan

Concentrations available for macitentan

10mg, 2.5mg