KREON 10000 150mg gastro-resistant capsules medication leaflet

Indicated for: exocrine pancreatic insufficiency; digestive disorders

Substance: pancreatin (pancreatic enzyme)

ATC: A09AA02 (Alimentary tract and metabolism | Digestives, incl. enzymes | Enzyme preparations)

Pancreatin is a mixture of digestive enzymes used to aid in the digestion of food when the pancreas does not produce enough enzymes. These enzymes include amylase (for carbohydrate digestion), lipase (for fat digestion), and protease (for protein digestion). Pancreatin is indicated for the treatment of exocrine pancreatic insufficiency associated with conditions such as cystic fibrosis, chronic pancreatitis, pancreatic cancer, or after pancreatic surgery.

Pancreatin is taken orally, usually in the form of capsules or tablets, during or immediately after meals to support food digestion. The dosage is adjusted based on the severity of enzyme deficiency and the patient's diet.

Side effects are rare but may include nausea, diarrhea, constipation, abdominal pain, or allergic reactions. Long-term use of high doses may increase the risk of hyperuricemia (elevated uric acid levels). It is important to use pancreatin as directed by a healthcare provider, and patients should avoid chewing the capsules to prevent irritation of the oral mucosa.