Indicated for: bleeding; coagulation disorders
Substance: coagulation factor VIII and von Willebrand factor (coagulation factor)
ATC: B02BD06 (Blood and blood forming organs | Vitamin k and other hemostatics | Blood coagulation factors)
The combination of coagulation factor VIII and von Willebrand factor is used in the treatment of hemophilia A and von Willebrand disease, two conditions involving blood clotting disorders. Factor VIII helps form the clot, while von Willebrand factor stabilizes factor VIII and facilitates platelet adhesion at the site of injury.
This combination is administered intravenously under medical supervision, with the dose adjusted according to the severity of the deficiency and the type of bleeding. Treatment can be given prophylactically or as needed, especially before surgeries or in case of trauma.
Side effects may include allergic reactions, fever, headaches, or, rarely, the development of antibodies that can reduce the effectiveness of the treatment. Careful monitoring of the patient is essential to quickly detect any adverse reactions and adjust the treatment if necessary.
Therapy with factor VIII and von Willebrand factor has significantly improved the quality of life for patients with bleeding disorders. Following medical advice and being informed about possible risks contribute to safe and effective treatment.