Indicated for: fungal infections
Substance: fluconazole (azole antifungal)
ATC: J02AC01 (Antiinfectives for systemic use | Antimycotics for systemic use | Triazole derivatives)
Fluconazole is an antifungal medication used to treat and prevent infections caused by fungi, particularly those caused by Candida species. It belongs to the triazole class and works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to the destruction of the fungi.
Fluconazole is indicated for the treatment of oral, esophageal, vaginal, and systemic candidiasis (invasive candidiasis) as well as cryptococcal meningitis. It is also used prophylactically in patients with weakened immune systems, such as those with HIV/AIDS, cancer, or undergoing immunosuppressive therapy.
The medication is administered orally (tablets or suspension) or intravenously, depending on the severity of the infection. The dosage and duration of treatment vary based on the type and location of the infection.
Common side effects include nausea, headache, abdominal pain, diarrhea, and skin rashes. In rare cases, it may cause severe liver reactions or serious allergic reactions. It is important to use fluconazole as prescribed by a healthcare provider, and patients should inform their doctor about other medications they are taking, as fluconazole can interact with many drugs, including anticoagulants and medications for heart rhythm.