BRUFEN 400mg tablets medication leaflet

M01AE01 • ibuprofen • Musculo-skeletal system | Antiinflammatory and antirheumatic products, non-steroids | Propionic acid derivatives

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and fever. It works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the production of prostaglandins, which are substances involved in inflammation, pain, and fever.

It is indicated for the relief of mild to moderate pain, such as headaches, dental pain, menstrual pain, muscle and joint pain, and for reducing fever associated with infections. It is also used in chronic inflammatory conditions such as rheumatoid arthritis or osteoarthritis.

Common side effects include nausea, abdominal discomfort, heartburn, and dizziness. Rarely, more serious reactions such as gastric ulcers, gastrointestinal bleeding, kidney dysfunction, or severe allergic reactions may occur. Long-term use or high doses may increase the risk of cardiovascular events, such as heart attack or stroke.

Ibuprofen should be taken as directed by a doctor or according to the package instructions, and the maximum daily dose should not be exceeded. It is recommended to take it with food to reduce the risk of stomach irritation. Patients with gastrointestinal, renal, or cardiovascular conditions should use ibuprofen with caution.

BRUFEN 400mg tablets BGP PRODUCTS, ibuprofen

General data about BRUFEN 400mg

Substance: ibuprofen

Date of last drug list: 10-04-2026

Commercial code: W62192005

Concentration: 400mg

Pharmaceutical form: tablets

Quantity: 30

Product type: original

Price: 23.19 RON

Prescription restrictions: P-6L - Medicines prescription that isn't retained in the pharmacy (can be renewed); the prescription can be used for 6 months from the moment of release.