AZACTAM 1000mg powder for injection medication leaflet

J01DF01 • aztreonam • Antiinfectives for systemic use | Other beta-lactam antibacterials | Monobactams

Aztreonam is a monobactam antibiotic used in the treatment of bacterial infections caused by aerobic gram-negative bacteria. It is effective against severe infections such as urinary tract infections, lower respiratory tract infections, septicemia, and intra-abdominal infections.

Aztreonam works by inhibiting bacterial cell wall synthesis, leading to bacterial destruction. It is administered intravenously or intramuscularly, depending on the severity of the infection and the patient's condition.

Common side effects include injection site reactions, skin rashes, nausea, and diarrhea. In rare cases, severe adverse reactions such as allergic reactions, pseudomembranous colitis, or liver function impairment may occur. It is important that aztreonam use is guided by bacterial sensitivity testing.

Aztreonam is a valuable therapeutic option for the treatment of severe bacterial infections, particularly in patients with allergies to other beta-lactam antibiotics such as penicillins or cephalosporins.