Indicated for: antithrombin deficiency
Substance: antithrombin III (coagulation factor)
ATC: B01AB02 (Blood and blood forming organs | Antithrombotic agents | Heparin group)
Antithrombin III is a natural plasma protein that plays a crucial role in regulating blood coagulation. It acts as an inhibitor of several enzymes in the coagulation cascade, including thrombin and factors Xa and IXa, thereby preventing excessive blood clot formation.
Antithrombin III deficiency can be hereditary or acquired and is associated with an increased risk of deep vein thrombosis and pulmonary embolism. In such cases, antithrombin III can be administered as a concentrate derived from human plasma or produced through recombinant technology.
Administration is done intravenously, usually in emergency situations or before surgical procedures in patients with antithrombin deficiency. Side effects are rare but may include allergic reactions or fever.
Antithrombin III is an essential medication for the prevention and treatment of thrombotic complications, helping to maintain hemostatic balance in the body.