Leaflet AMPIPLUS 1000mg / 500mg powder for injection / infusion solution


Indicated for: bacterial infections

Route of administration: injectable / infusion

Substance: ampicillin + sulbactam (penicillin antibiotic + beta-lactam antibiotic)

ATC: J01CR01 (Antiinfectives for systemic use | Beta-lactam antibacterials, penicillins | Combinations of penicillins, incl. beta-lactamase inhibitors)

Ampicillin + sulbactam is a combination of an antibiotic and a beta-lactamase inhibitor used to treat resistant bacterial infections. Sulbactam protects ampicillin from beta-lactamase enzymes produced by bacteria, allowing ampicillin to remain effective against resistant strains.

This combination is indicated for upper and lower respiratory tract infections (sinusitis, pneumonia), urinary tract infections, intra-abdominal infections, skin and soft tissue infections, as well as gynecological and septic infections.

Ampicillin + sulbactam is available as an injectable solution and is administered intravenously or intramuscularly, usually in a hospital setting under medical supervision.

Side effects may include nausea, diarrhea, skin rashes, pain at the injection site, and, rarely, severe allergic reactions (anaphylaxis). It is important to take it as prescribed by a doctor and to complete the full course of treatment to prevent bacterial resistance.

General data about AMPIPLUS 1000mg / 500mg

  • Substance: ampicillin + sulbactam
  • Date of last drug list: 01-05-2026
  • Commercial code: W58901002
  • Concentration: 1000mg / 500mg
  • Pharmaceutical form: powder for injection / infusion solution
  • Quantity: 50
  • Product type: generic
  • Price: 946.84 RON
  • Prescription restrictions: P-RF - Medicines prescription that is retained in the pharmacy (not renewable).

Marketing authorisation

  • Manufacturer: ANTIBIOTICE S.A. - ROMANIA
  • Holder: ANTIBIOTICE S.A. - ROMANIA
  • Number: 4772/2012/02
  • Shelf life: 3 years-after packing for marketing; after reconstitution-it is used immediately

Concentrations available for ampicillin + sulbactam

  • 1000mg/500mg
  • 1g/0.5g
  • 1g/500mg
  • 2000mg/1000mg
  • 2g/1g
  • 500mg/250mg

Compensation lists for AMPIPLUS 1000mg / 500mg Antibiotice

B - Sublist B with 50% discount from the reference price

Price

Copayment

Patient

946.84 RON

463.87 RON

482.97 RON

NHP 1.A (C2) - People with HIV/AIDS and post-exposure treatment

Price

Copayment

Patient

946.84 RON

946.84 RON

0.00 RON