Leaflet ABACAVIR SANDOZ 300mg film-coated tablets

Indicated for: HIV-1 infection

Route of administration: oral

Substance: abacavir (nucleoside/nucleotide reverse transcriptase inhibitor)

ATC: J05AF06 (Antiinfectives for systemic use | Direct acting antivirals | Nucleoside and nucleotide reverse transcriptase inhibitors)

Precautions:
Breastfeeding warning
Breastfeeding warning

Use during breastfeeding only on medical advice.

Pregnancy warning
Pregnancy warning

Use during pregnancy only on medical advice.

Severe skin reactions
Severe skin reactions

Stop taking the medicine and seek urgent medical help if a severe rash occurs.

Genetic test recommended
Genetic test recommended

A genetic test may be needed before treatment.

Abacavir is a medication used to treat HIV/AIDS.
Similar to other nucleoside analog reverse-transcriptase inhibitors (NRTIs), abacavir is used together with other HIV medications, and is not recommended by itself.
It is taken by mouth as a tablet or solution and may be used in children over the age of three months.

Abacavir was patented in 1988, and approved for use in the United States in 1998.
It is on the World Health Organization's List of Essential Medicines.
It is available as a generic medication.
Abacavir is used together with other HIV medications, such as abacavir/lamivudine/zidovudine, abacavir/dolutegravir/lamivudine, and abacavir/lamivudine.
The combination abacavir/lamivudine is an essential medicine.

Abacavir is a nucleoside reverse transcriptase inhibitor that inhibits viral replication.
It is a guanosine analogue that is phosphorylated to carbovir triphosphate (CBV-TP).
CBV-TP competes with the viral molecules and is incorporated into the viral DNA.
Once CBV-TP is integrated into the viral DNA, transcription and HIV reverse transcriptase is inhibited.

General data about ABACAVIR SANDOZ 300mg

  • Substance: abacavir
  • Date of latest medicines list: 01-09-2016
  • Product code: W62867001
  • Concentration: 300mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 60
  • Product type: Generic medicine
  • Prescription status: P-RF - Medicines dispensed with a medical prescription that is retained by the pharmacy and cannot be renewed.

Marketing authorisation

  • Manufacturer: SALUTAS PHARMA GMBH - GERMANIA
  • Holder: SANDOZ S.R.L. - ROMANIA
  • Number: 9072/2016/01
  • Shelf life: 2 years

Pharmaceutical forms available for abacavir

Concentrations available for abacavir

  • 20mg/ml
  • 300mg