Leaflet DETRALEX 1000mg film-coated tablets

Indicated for: chronic venous insufficiency; capillary fragility

Route of administration: oral

Substance: diosmin (vasodilator)

ATC: C05CA53 (Cardiovascular system | Capillary stabilizing agents | Bioflavonoids)

Precautions:
Dizziness / vertigo
Dizziness / vertigo

This medicine may cause dizziness or vertigo.

Hypotension / fall risk
Hypotension / fall risk

May lower blood pressure and increase the risk of falls.

Diosmin is a natural flavonoid used in the treatment of venous and lymphatic disorders. It is commonly prescribed to alleviate symptoms of chronic venous insufficiency, such as pain, heaviness in the legs, swelling (edema), and nighttime cramps. It is also used in the treatment of acute or chronic hemorrhoids.

Diosmin works by increasing venous tone, reducing capillary fragility, and improving lymphatic drainage. It helps reduce inflammation and improve blood circulation, making it effective in preventing blood stagnation in affected veins.

It is used both as a long-term treatment for venous insufficiency and as a short-term therapy for acute hemorrhoidal crises. Diosmin is often combined with hesperidin, another flavonoid, to enhance the effectiveness of the treatment.

Side effects are rare and usually mild. They may include nausea, diarrhea, abdominal pain, or skin allergic reactions. In general, diosmin is well-tolerated by most patients.

Patients should follow their doctor’s recommendations regarding dosage and treatment duration. It is important to adopt a healthy lifestyle, including regular physical activity, avoiding prolonged standing or sitting, and maintaining an optimal body weight to support the effectiveness of the treatment.

DETRALEX 1000mg film-coated tablets SERVIER, diosmin

General data about DETRALEX 1000mg

  • Substance: diosmin
  • Date of latest medicines list: 01-06-2026
  • Product code: W66812002
  • Concentration: 1000mg
  • Pharmaceutical form: film-coated tablets
  • Quantity: 30
  • Product type: Original
  • Price: 65.63 RON
  • Prescription status: P-6L - Medicines dispensed with a medical prescription that is not retained by the pharmacy and may be renewed; the prescription may be used for 6 months from the date of issue.

Marketing authorisation

  • Manufacturer: SERVIER (IRELAND) INDUSTRIES LTD. - IRLANDA
  • Holder: LES LABORATOIRES SERVIER - FRANTA
  • Number: 13151/2020/02
  • Shelf life: 4 years

Pharmaceutical forms available for diosmin

Concentrations available for diosmin

  • 1000mg
  • 450mg/50mg
  • 500mg
  • 600mg

Compensation lists for DETRALEX 1000mg Servier

D - Sublist D with 20% discount from the reference price

Price

Copayment

Patient

65.63 RON

13.13 RON

52.50 RON